Teratogenic activity of 2-amino-1,3,4-thiadiazole hydrochloride in Wistar rats and the protection afforded by nicotinamide
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منابع مشابه
Teratogenic activity of 2-amino-1,3,4-thiadiazole hydrochloride in Wistar rats and the protection afforded by nicotinamide.
Pregnant Wistar rats were each injected once ip with various doses of 2-amino-l,3,4-thiadiazole hydrochloride (ATDA) at days 1-16 of gestation (sperm day = day 0). The optimal teratogenic dose was determined to be 100 mg/kg and this dose was employed throughout the experiment, At autopsy at day 20 resorptions and malformations were found in all litters from treated females. Two periods of incre...
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ژورنال
عنوان ژورنال: Teratology
سال: 1973
ISSN: 0040-3709,1096-9926
DOI: 10.1002/tera.1420070110